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FBXO17 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | ||||
| AP17261b | DISCONTINED INQUIRE CLICK INQUIRE Add to cart | |||
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
FBXO17 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | Q96EF6 |
| Other Accession | Q9QZM8, NP_680474.1, NP_079183.4 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 31479 Da |
FBXO17 Antibody (C-term) - Additional info | |
| Gene ID 115290 | |
| Other Names FBXO17; FBG4; FBX17; FBX26; FBXO26; F-box only protein 17; F-box only protein 26 | |
| Target/Specificity This FBXO17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-254 amino acids from the C-terminal region of human FBXO17. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions FBXO17 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
FBXO17 Antibody (C-term) - Protein Information | |
| Name FBXO17 | |
| Synonyms FBG4, FBX17, FBX26, FBXO26 | |
| Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins | |
| Tissue Location Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain | |
FBXO17 Antibody (C-term) - Related products
FBXO17 Antibody (C-term) - Application data
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FBXO17 Antibody (C-term) (Cat. #AP17261b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FBXO17 antibody detected the FBXO17 protein (arrow).
FBXO17 Antibody (C-term) - Research Areas
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BACKGROUND
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing of this gene results in 2 transcript variants encoding different isoforms.
REFERENCES
Glenn, K.A., et al. J. Biol. Chem. 283(19):12717-12729(2008) Szafranski, K., et al. Genome Biol. 8 (8), R154 (2007) : Ilyin, G.P., et al. Gene 296 (1-2), 11-20 (2002) : Kipreos, E.T., et al. Genome Biol. 1 (5), REVIEWS3002 (2000) : Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
