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PGBD1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96JS3 |
| Other Accession | NP_001171672.1, NP_115896.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 92515 Da |
| Antigen Region | 347-375 aa |
| Gene ID | 84547 |
|---|---|
| Other Names | PiggyBac transposable element-derived protein 1, Cerebral protein 4, PGBD1 |
| Target/Specificity | This PGBD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-375 amino acids from the Central region of human PGBD1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PGBD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PGBD1 |
|---|
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Provided below are standard protocols that you may find useful for product applications.
Background
The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
References
Li, T., et al. Biol. Psychiatry 68(7):671-673(2010)
Corneveaux, J.J., et al. Hum. Mol. Genet. 19(16):3295-3301(2010)
Schjeide, B.M., et al. Neurogenetics 10(1):19-25(2009)
Sarkar, A., et al. Mol. Genet. Genomics 270(2):173-180(2003)
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