|Application ||WB, E|
|Calculated MW||114192 Da|
|Antigen Region||927-955 aa|
|Other Names||Synaptonemal complex protein 1, SCP-1, Cancer/testis antigen 8, CT8, SYCP1, SCP1|
|Target/Specificity||This SYCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 927-955 amino acids from the C-terminal region of human SYCP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SYCP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.|
|Cellular Location||Nucleus. Chromosome. Note=In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C- terminus extends well into the lateral domain of the synaptonemal complex (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Neumann, F., et al. Blood 106(9):3105-3113(2005)
Costa, Y., et al. J. Cell. Sci. 118 (PT 12), 2755-2762 (2005) :
Eichmuller, S., et al. Proc. Natl. Acad. Sci. U.S.A. 98(2):629-634(2001)
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