|Application ||IF, WB, E|
|Other Accession||Q8R3L2, NP_055787.1|
|Calculated MW||76667 Da|
|Antigen Region||186-215 aa|
|Other Names||Transcription factor 25, TCF-25, Nuclear localized protein 1, TCF25, KIAA1049, NULP1|
|Target/Specificity||This TCF25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the N-terminal region of human TCF25.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TCF25 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.|
|Cellular Location||Nucleus. Note=Some staining in the cytosol|
|Tissue Location||In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM].
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Steen, H., et al. Biochem. Biophys. Res. Commun. 366(2):432-437(2008)
Cai, Z., et al. Biochem. Biophys. Res. Commun. 343(3):973-981(2006)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.