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PRDM5 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRDM5 Antibody (N-term) AP17297A
    PRDM5 Antibody (N-term) (Cat. #AP17297a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PRDM5 antibody detected the PRDM5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQX1
Other Accession NP_061169.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 73090 Da
Antigen Region 132-160 aa
Additional Information
Gene ID 11107
Other Names PR domain zinc finger protein 5, 211-, PR domain-containing protein 5, PRDM5, PFM2
Target/Specificity This PRDM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the N-terminal region of human PRDM5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRDM5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDM5
Synonyms PFM2
Function Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.
Cellular Location Nucleus
Tissue Location Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues.
Citations (0)

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The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis.


Cheng, H.Y., et al. J. Cancer Res. Clin. Oncol. 136(12):1821-1825(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Duan, Z., et al. Mol. Cell. Biol. 27(19):6889-6902(2007)
Watanabe, Y., et al. Clin. Cancer Res. 13(16):4786-4794(2007)

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Cat# AP17297A
(40 western blots)
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