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Mouse Taok3 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Taok3 Antibody (N-term) AP17319a
    Mouse Taok3 Antibody (N-term) (Cat. #AP17319a) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Taok3 antibody detected the Taok3 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8BYC6
Other Accession NP_001074777.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 105336 Da
Antigen Region 257-284 aa
Additional Information
Gene ID 330177
Other Names Serine/threonine-protein kinase TAO3, Thousand and one amino acid protein 3, Taok3
Target/Specificity This Mouse Taok3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-284 amino acids from the N-terminal region of mouse Taok3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Taok3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Taok3
Function Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF) (By similarity).
Cellular Location Cytoplasm.
Research Areas
Citations (0)
citation

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Background

Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK (By similarity).

References

Stryke, D., et al. Nucleic Acids Res. 31(1):278-281(2003)

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$ 365.00
$ 140.00
Cat# AP17319a
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