|Application ||WB, E|
|Other Accession||Q9ERN0, NP_005688.2|
|Calculated MW||36649 Da|
|Antigen Region||119-147 aa|
|Other Names||Secretory carrier-associated membrane protein 2, Secretory carrier membrane protein 2, SCAMP2|
|Target/Specificity||This SCAMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the Central region of human SCAMP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SCAMP2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.|
|Cellular Location||Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Diering, G.H., et al. J. Biol. Chem. 284(20):13892-13903(2009)
Liao, H., et al. Biochemistry 46(38):10909-10920(2007)
Muller, H.K., et al. J. Biol. Chem. 281(39):28901-28909(2006)
Stelzl, U., et al. Cell 122(6):957-968(2005)
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