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TAS2R10 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TAS2R10 Antibody (Center) AP17340c
    TAS2R10 Antibody (Center) (Cat. #AP17340c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TAS2R10 antibody detected the TAS2R10 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NYW0
Other Accession NP_076410.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35365 Da
Antigen Region 134-160 aa
Additional Information
Gene ID 50839
Other Names Taste receptor type 2 member 10, T2R10, Taste receptor family B member 2, TRB2, TAS2R10
Target/Specificity This TAS2R10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 amino acids from the Central region of human TAS2R10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTAS2R10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAS2R10
Function Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells
Research Areas
Citations (0)
citation

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Background

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.

References

Go, Y., et al. Genetics 170(1):313-326(2005)
Mueller, K.L., et al. Nature 434(7030):225-229(2005)
Fischer, A., et al. Mol. Biol. Evol. 22(3):432-436(2005)
Zhang, Y., et al. Cell 112(3):293-301(2003)
Montmayeur, J.P., et al. Curr. Opin. Neurobiol. 12(4):366-371(2002)

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$ 365.00
$ 140.00
Cat# AP17340c
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