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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   LAS1L Antibody (C-term)   

LAS1L Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LAS1L Antibody (C-term) AP17345B
    LAS1L Antibody (C-term) (Cat. #AP17345b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LAS1L antibody detected the LAS1L protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y4W2
Other Accession NP_001164120.1, NP_001164121.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 83065 Da
Antigen Region 639-665 aa
Additional Information
Gene ID 81887
Other Names Ribosomal biogenesis protein LAS1L, Protein LAS1 homolog, LAS1L
Target/Specificity This LAS1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-665 amino acids from the C-terminal region of human LAS1L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLAS1L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LAS1L
Function Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Cellular Location Nucleus, nucleolus Nucleus, nucleoplasm. Cytoplasm Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export
Research Areas
Citations (0)

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The function of LAS1L has not been determined.


Castle, C.D., et al. Mol. Cell. Biol. 30(18):4404-4414(2010)
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)

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$ 295.00
$ 99.00
Cat# AP17345B
(40 western blots)
Availability: In Stock
Bulk Size
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