|Application ||WB, E|
|Calculated MW||71422 Da|
|Antigen Region||205-233 aa|
|Other Names||Zinc finger protein 131, ZNF131|
|Target/Specificity||This ZNF131 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the Central region of human ZNF131.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF131 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.|
|Cellular Location||Nucleus Note=Sumoylation does not affect nuclear localization|
|Tissue Location||Predominant expression is found in different brain areas such as the occipital and temporal lobe, the nucleus caudatus, hippocampus, and the cerebellum as well as in testis and thymus.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ZNF131 may be involved in transcriptional regulation. Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity).
Han, X., et al. BMC Genomics 9, 476 (2008) :
Donaldson, N.S., et al. Biochim. Biophys. Acta 1773(4):546-555(2007)
Schmutz, J., et al. Nature 431(7006):268-274(2004)
Trappe, R., et al. Biochem. Biophys. Res. Commun. 296(2):319-327(2002)
Tommerup, N., et al. Genomics 27(2):259-264(1995)
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