|Application ||WB, E|
|Calculated MW||71422 Da|
|Antigen Region||205-233 aa|
|Other Names||Zinc finger protein 131, ZNF131|
|Target/Specificity||This ZNF131 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the Central region of human ZNF131.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF131 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.|
|Cellular Location||Nucleus Note=Sumoylation does not affect nuclear localization|
|Tissue Location||Predominant expression is found in different brain areas such as the occipital and temporal lobe, the nucleus caudatus, hippocampus, and the cerebellum as well as in testis and thymus.|
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Provided below are standard protocols that you may find useful for product applications.
ZNF131 may be involved in transcriptional regulation. Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity).
Han, X., et al. BMC Genomics 9, 476 (2008) :
Donaldson, N.S., et al. Biochim. Biophys. Acta 1773(4):546-555(2007)
Schmutz, J., et al. Nature 431(7006):268-274(2004)
Trappe, R., et al. Biochem. Biophys. Res. Commun. 296(2):319-327(2002)
Tommerup, N., et al. Genomics 27(2):259-264(1995)
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