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LCORL Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LCORL Antibody (Center) AP17352c
    Anti-LCORL Antibody (Center) at 1:1000 dilution + T47D whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 67 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N3X6
Other Accession NP_710153.2, NP_001159611.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 66964 Da
Antigen Region 306-334 aa
Additional Information
Gene ID 254251
Other Names Ligand-dependent nuclear receptor corepressor-like protein, LCoR-like protein, LCORL
Target/Specificity This LCORL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the Central region of human LCORL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLCORL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LCORL
Function May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00320}.
Citations (0)
citation

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Background

This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
Liu, J.Z., et al. Twin Res Hum Genet 13(2):179-193(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) :

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$ 365.00
$ 140.00
Cat# AP17352c
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