LCORL Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8N3X6 |
Other Accession | NP_710153.2, NP_001159611.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 66964 Da |
Antigen Region | 306-334 aa |
Gene ID | 254251 |
---|---|
Other Names | Ligand-dependent nuclear receptor corepressor-like protein, LCoR-like protein, LCORL |
Target/Specificity | This LCORL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the Central region of human LCORL. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LCORL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LCORL |
---|---|
Function | May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00320}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
Liu, J.Z., et al. Twin Res Hum Genet 13(2):179-193(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) :
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