|Application ||WB, E|
|Other Accession||Q8VHH5, NP_001036000.1, NP_114152.3|
|Calculated MW||95044 Da|
|Antigen Region||190-217 aa|
|Other Names||Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3, AGAP-3, CRAM-associated GTPase, CRAG, Centaurin-gamma-3, Cnt-g3, MR1-interacting protein, MRIP-1, AGAP3, CENTG3|
|Target/Specificity||This AGAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-217 amino acids from the N-terminal region of human AGAP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AGAP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway.|
|Cellular Location||Cytoplasm. Note=In cells upon oxidative stress or in brains of Machado-Joseph disease patients, translocates to PML nuclear bodies|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway.
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Qin, Q., et al. J. Cell Biol. 172(4):497-504(2006)
Meurer, S., et al. J. Biol. Chem. 279(47):49346-49354(2004)
Surks, H.K., et al. J. Biol. Chem. 278(51):51484-51493(2003)
Xia, C., et al. Mol. Cell. Biol. 23(7):2476-2488(2003)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.