HMGN5 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P82970 |
Other Accession | NP_110390.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 31525 Da |
Antigen Region | 60-86 aa |
Gene ID | 79366 |
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Other Names | High mobility group nucleosome-binding domain-containing protein 5, Nucleosome-binding protein 1, HMGN5, NSBP1 |
Target/Specificity | This HMGN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-86 amino acids from the N-terminal region of human HMGN5. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HMGN5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HMGN5 |
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Synonyms | NSBP1 |
Function | Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. |
Cellular Location | Nucleus. Note=Associates with nucleosomes in euchromatin and is largely excluded from constitutive heterochromatin. |
Tissue Location | Ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein.
References
Rochman, M., et al. Biochim. Biophys. Acta 1799 (1-2), 86-92 (2010) :
Rochman, M., et al. Mol. Cell 35(5):642-656(2009)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
King, L.M., et al. Genomics 71(2):163-173(2001)
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