|Application ||WB, E|
|Calculated MW||39666 Da|
|Antigen Region||1-30 aa|
|Other Names||Fasciculation and elongation protein zeta-2, Zygin II, Zygin-2, FEZ2|
|Target/Specificity||This FEZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FEZ2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FEZ2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in axonal outgrowth and fasciculation.|
|Tissue Location||Expressed in nonneural tissues, such as heart, lung, spleen, muscle, testis, placenta and melanocytes|
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Provided below are standard protocols that you may find useful for product applications.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Assmann, E.M., et al. J. Biol. Chem. 281(15):9869-9881(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Fujita, T., et al. Biochem. Biophys. Res. Commun. 313(3):738-744(2004)
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