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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KCTD13 Antibody (C-term)   

KCTD13 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - KCTD13 Antibody (C-term) AP17375b
    KCTD13 Antibody (C-term) (Cat. #AP17375b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KCTD13 antibody detected the KCTD13 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8WZ19
Other Accession Q7TPL3, Q922M3, Q9H3F6, Q5EAX2, Q7TNY1, O70479, Q13829, Q5F3E8, Q8BGV7, Q2T9W0, NP_849194.1
Reactivity Human
Predicted Bovine, Mouse, Chicken, Rat, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36357 Da
Antigen Region 229-258 aa
Additional Information
Gene ID 253980
Other Names BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1, hBACURD1, BTB/POZ domain-containing protein KCTD13, Polymerase delta-interacting protein 1, TNFAIP1-like protein, KCTD13, BACURD1, PDIP1, POLDIP1
Target/Specificity This KCTD13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-258 amino acids from the C-terminal region of human KCTD13.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCTD13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCTD13
Synonyms BACURD1, PDIP1, POLDIP1
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.
Cellular Location Nucleus.
Tissue Location Expressed in a wide variety of tissues.
Research Areas
Citations (0)

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Background

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.

References

Chen, Y., et al. Mol. Cell 35(6):841-855(2009)
Tomaru, T., et al. Endocrinology 147(1):377-388(2006)
Zhou, J., et al. J. Exp. Zoolog. Part A Comp. Exp. Biol. 303(3):227-240(2005)
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Kutsenko, A.S., et al. Nucleic Acids Res. 30(14):3163-3170(2002)

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$ 295.00
$ 99.00
Cat# AP17375b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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