|Application ||WB, E|
|Other Accession||Q3UTQ7, A2BID7, NP_064613.2, NP_955469.1|
|Calculated MW||130136 Da|
|Antigen Region||744-772 aa|
|Other Names||PR domain zinc finger protein 10, 211-, PR domain-containing protein 10, Tristanin, PRDM10, KIAA1231, PFM7, TRIS|
|Target/Specificity||This PRDM10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids from the Central region of human PRDM10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRDM10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1231, PFM7, TRIS|
|Function||May be involved in transcriptional regulation.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Bhatti, P., et al. Radiat. Res. 173(2):214-224(2010)
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Siegel, D.A., et al. Int. J. Dev. Neurosci. 20 (3-5), 373-389 (2002) :
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