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ARL6IP5 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ARL6IP5 Antibody (Center) AP17402c
    ARL6IP5 Antibody (Center) (Cat. #AP17402c) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ARL6IP5 antibody detected the ARL6IP5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75915
Other Accession NP_006398.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21615 Da
Antigen Region 70-99 aa
Additional Information
Gene ID 10550
Other Names PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, ARL-6-interacting protein 5, Aip-5, Cytoskeleton-related vitamin A-responsive protein, Dermal papilla-derived protein 11, GTRAP3-18, Glutamate transporter EAAC1-interacting protein, JM5, Prenylated Rab acceptor protein 2, Protein JWa, Putative MAPK-activating protein PM27, ARL6IP5, DERP11, JWA, PRA2, PRAF3
Target/Specificity This ARL6IP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the Central region of human ARL6IP5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARL6IP5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARL6IP5
Synonyms DERP11, JWA, PRA2, PRAF3
Function Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein Cytoplasm. Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules (By similarity)
Research Areas
Citations (0)

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Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.


Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34(5):840-852(2010)
Akiduki, S., et al. J. Biol. Chem. 283(46):31323-31332(2008)
Ruggiero, A.M., et al. J. Biol. Chem. 283(10):6175-6183(2008)
Watabe, M., et al. Mol. Pharmacol. 72(5):1103-1110(2007)
Zhu, Y.J., et al. J. Toxicol. Environ. Health Part A 70(11):895-900(2007)

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Cat# AP17402c
(40 western blots)
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