|Application ||WB, E|
|Other Accession||NP_995309.2, NP_001160010.1|
|Calculated MW||10792 Da|
|Antigen Region||19-47 aa|
|Other Names||Leukocyte-specific transcript 1 protein, Protein B144, LST1, B144|
|Target/Specificity||This LST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the Central region of human LST1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LST1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.|
|Cellular Location||Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm|
|Tissue Location||Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain|
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Provided below are standard protocols that you may find useful for product applications.
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Man, M., et al. J Clin Pharmacol 50(8):929-940(2010)
Rojas, J., et al. Ophthalmology (2010) In press :
Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :
Ovsyannikova, I.G., et al. PLoS ONE 5 (7), E11806 (2010) :
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