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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   SRA1 Antibody (C-term)   

SRA1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SRA1 Antibody (C-term) AP17404b
    SRA1 Antibody (C-term) (Cat. #AP17404b) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the SRA1 antibody detected the SRA1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HD15
Other Accession NP_001030312.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25673 Da
Antigen Region 193-222 aa
Additional Information
Gene ID 10011
Other Names Steroid receptor RNA activator 1, Steroid receptor RNA activator protein, SRAP, SRA1 (HGNC:11281)
Target/Specificity This SRA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from the C-terminal region of human SRA1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSRA1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRA1 (HGNC:11281)
Function Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
Cellular Location Nucleus. Cytoplasm
Tissue Location Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up- regulated in human tumors of the breast, ovary, and uterus
Research Areas
Citations (0)

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This gene is involved in transcriptional coactivation by steroid receptors. There is currently data suggesting this gene encodes both a non-coding RNA that functions as part of a ribonucleoprotein complex and a protein coding mRNA. Increased expression of both the transcript and the protein is associated with cancer.


Yao, H., et al. Genes Dev. 24(22):2543-2555(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Beauvillain, C., et al. J. Hepatol. 52(5):644-651(2010)
Foulds, C.E., et al. Mol. Endocrinol. 24(5):1090-1105(2010)
Chooniedass-Kothari, S., et al. FEBS Lett. 584(6):1174-1180(2010)

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$ 295.00
$ 99.00
Cat# AP17404b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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