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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LY96 Antibody (C-term)   

LY96 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LY96 Antibody (C-term) AP17412b
    LY96 Antibody (C-term) (Cat. #AP17412b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LY96 antibody detected the LY96 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6Y9
Other Accession NP_056179.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 18546 Da
Antigen Region 103-132 aa
Additional Information
Gene ID 23643
Other Names Lymphocyte antigen 96, Ly-96, ESOP-1, Protein MD-2, LY96, ESOP1, MD2
Target/Specificity This LY96 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the C-terminal region of human LY96.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLY96 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LY96
Synonyms ESOP1, MD2
Function Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
Cellular Location Secreted, extracellular space.
Research Areas
Citations (0)

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This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.


Meng, J., et al. J. Biol. Chem. 285(36):27935-27943(2010)
Gray, P., et al. J. Immunol. 184(11):6359-6366(2010)
Salvesen, B., et al. Mol. Immunol. 47(6):1226-1234(2010)
Ohnishi, T., et al. Microbiol. Immunol. 54(2):74-80(2010)
Xue, Y., et al. Genet. Mol. Res. 9(3):1584-1590(2010)

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$ 295.00
$ 99.00
Cat# AP17412b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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