HLF Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q16534 |
Other Accession | Q64709, Q8BW74, NP_002117.1 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33199 Da |
Antigen Region | 204-232 aa |
Gene ID | 3131 |
---|---|
Other Names | Hepatic leukemia factor, HLF |
Target/Specificity | This HLF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the C-terminal region of human HLF. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HLF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HLF |
---|---|
Cellular Location | Nucleus. |
Tissue Location | Highly expressed in liver; lower levels in lung and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
References
Hirose, K., et al. Blood 116(6):962-970(2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Otto, T., et al. Endocrinology 149(5):2241-2250(2008)
Inukai, T., et al. Leukemia 21(2):288-296(2007)
He, J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22(5):551-553(2005)
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