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RAP2B Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RAP2B Antibody (Center) AP17426c
    RAP2B Antibody (Center) (Cat. #AP17426c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the RAP2B antibody detected the RAP2B protein (arrow).
  • WB - RAP2B Antibody (Center) AP17426c
    Western blot analysis of RAP2B (arrow) using rabbit polyclonal RAP2B Antibody (Center) (Cat. #AP17426c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RAP2B gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61225
Other Accession P61227, P61226, Q06AU2, NP_002877.2
Reactivity Human
Predicted Pig, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20504 Da
Antigen Region 102-129 aa
Additional Information
Gene ID 5912
Other Names Ras-related protein Rap-2b, RAP2B
Target/Specificity This RAP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-129 amino acids from the Central region of human RAP2B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAP2B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAP2B
Function Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
Cellular Location Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Associated with red blood cells-released vesicles
Tissue Location Expressed in red blood cells (at protein level).
Research Areas
Citations (0)

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This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Martins-de-Souza, D., et al. J Psychiatr Res (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Canobbio, I., et al. Cell. Signal. 20(9):1662-1670(2008)
Liu, Y., et al. Lung Cancer 56(3):307-317(2007)

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$ 295.00
$ 99.00
Cat# AP17426c
(40 western blots)
Availability: In Stock
Bulk Size
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