ABLIM3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O94929 |
Other Accession | Q69ZX8, NP_055760.1 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 77802 Da |
Antigen Region | 613-641 aa |
Gene ID | 22885 |
---|---|
Other Names | Actin-binding LIM protein 3, abLIM-3, Actin-binding LIM protein family member 3, ABLIM3, KIAA0843 |
Target/Specificity | This ABLIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ABLIM3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ABLIM3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ABLIM3 |
---|---|
Synonyms | KIAA0843 |
Function | May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. |
Cellular Location | Cytoplasm. |
Tissue Location | Expressed predominantly in heart and brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer (Krupp et al., 2006 [PubMed 16328021]).
References
Barrientos, T., et al. J. Biol. Chem. 282(11):8393-8403(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Krupp, M., et al. Int. J. Mol. Med. 17(1):129-133(2006)
Zheng, B., et al. Biochim. Biophys. Acta 1690(1):1-10(2004)
Yamada, S., et al. Oncogene 23(35):5901-5911(2004)
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