|Application ||WB, E|
|Calculated MW||83157 Da|
|Antigen Region||191-218 aa|
|Other Names||Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Protein-tyrosine kinase Mpk-9, Ribosomal S6 kinase 3, RSK-3, pp90RSK3, Rps6ka2, Mapkapk1c, Rsk3|
|Target/Specificity||This Mouse Rps6ka2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the N-terminal region of mouse Rps6ka2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Rps6ka2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells (By similarity).|
|Cellular Location||Nucleus. Cytoplasm|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB (By similarity).
Bae, G.U., et al. Mol. Biol. Cell 20(23):4920-4931(2009)
Fischer, M., et al. Mol. Cell. Neurosci. 42(2):134-141(2009)
Cho, Y.Y., et al. Cancer Res. 67(17):8104-8112(2007)
Panasyuk, G., et al. J. Biol. Chem. 281(42):31188-31201(2006)
Maekawa, N., et al. Circulation 113(21):2516-2523(2006)
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