|Application ||WB, E|
|Other Accession||Q63285, Q8TAS1, NP_034763.3|
|Calculated MW||46489 Da|
|Antigen Region||1-30 aa|
|Other Names||Serine/threonine-protein kinase Kist, Kinase interacting with stathmin, PAM COOH-terminal interactor protein 2, P-CIP2, U2AF homology motif kinase 1, Uhmk1, Kis, Kist|
|Target/Specificity||This Mouse Uhmk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Uhmk1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Uhmk1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).|
|Cellular Location||Nucleus. Note=Mostly nuclear|
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Provided below are standard protocols that you may find useful for product applications.
Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).
Francone, V.P., et al. Mol. Endocrinol. 24(8):1543-1558(2010)
Cambray, S., et al. Mol. Cell. Biol. 29(3):726-735(2009)
Langenickel, T.H., et al. J. Clin. Invest. 118(12):3848-3859(2008)
McKee, A.E., et al. BMC Dev. Biol. 5, 14 (2005) :
Cobellis, G., et al. Nucleic Acids Res. 33 (4), E44 (2005) :
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