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AP4M1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AP4M1 Antibody (Center) AP17446c
    AP4M1 Antibody (Center) (Cat. #AP17446c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the AP4M1 antibody detected the AP4M1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00189
Other Accession Q2PWT8, Q9JKC7, Q29RY8, NP_004713.2
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49977 Da
Antigen Region 223-251 aa
Additional Information
Gene ID 9179
Other Names AP-4 complex subunit mu-1, AP-4 adaptor complex mu subunit, Adaptor-related protein complex 4 subunit mu-1, Mu subunit of AP-4, Mu-adaptin-related protein 2, mu-ARP2, Mu4-adaptin, mu4, AP4M1, MUARP2
Target/Specificity This AP4M1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the Central region of human AP4M1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAP4M1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AP4M1
Synonyms MUARP2
Function Component of the AP-4 complex, a novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal- lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network (TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.
Cellular Location Golgi apparatus, trans-Golgi network. Membrane, coated pit. Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells
Tissue Location Ubiquitous. Highly expressed in testis and lowly expressed in brain and lung.
Research Areas
Citations (0)

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This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.


Verkerk, A.J., et al. Am. J. Hum. Genet. 85(1):40-52(2009)
Matsuda, S., et al. Neuron 57(5):730-745(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Simmen, T., et al. Nat. Cell Biol. 4(2):154-159(2002)
Boehm, M., et al. EMBO J. 20(22):6265-6276(2001)

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$ 295.00
$ 99.00
Cat# AP17446c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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