|Application ||WB, E|
|Calculated MW||82682 Da|
|Antigen Region||188-215 aa|
|Other Names||Serologically defined colon cancer antigen 8, Antigen NY-CO-8, Centrosomal colon cancer autoantigen protein, hCCCAP, SDCCAG8, CCCAP, NPHP10|
|Target/Specificity||This SDCCAG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the N-terminal region of human SDCCAG8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SDCCAG8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell junction Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle|
|Tissue Location||Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy.
Otto, E.A., et al. Nat. Genet. 42(10):840-850(2010)
Scherag, A., et al. PLoS Genet. 6 (4), E1000916 (2010) :
McCauley, J.L., et al. Genes Immun. 10(7):624-630(2009)
Kenedy, A.A., et al. Gene 303, 35-46 (2003) :
Scanlan, M.J., et al. Int. J. Cancer 76(5):652-658(1998)
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