|Application ||WB, E|
|Other Accession||NP_001159884.1, NP_071421.1|
|Calculated MW||49674 Da|
|Antigen Region||405-431 aa|
|Other Names||SPARC-related modular calcium-binding protein 2, Secreted modular calcium-binding protein 2, SMOC-2, Smooth muscle-associated protein 2, SMAP-2, SMOC2, SMAP2|
|Target/Specificity||This SMOC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-431 amino acids from the C-terminal region of human SMOC2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SMOC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes matrix assembly and cell adhesiveness (By similarity). Can stimulate endothelial cell proliferation, migration, as well as angiogenesis.|
|Cellular Location||Secreted, extracellular space, extracellular matrix, basement membrane|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Birlea, S.A., et al. J. Invest. Dermatol. 130(3):798-803(2010)
Wilk, J.B., et al. Am. J. Respir. Crit. Care Med. 175(6):554-560(2007)
Rocnik, E.F., et al. J. Biol. Chem. 281(32):22855-22864(2006)
Vannahme, C., et al. Biochem. J. 373 (PT 3), 805-814 (2003) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.