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OSBPL6 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - OSBPL6 Antibody (C-term) AP17475b
    OSBPL6 Antibody (C-term) (Cat. #AP17475b) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the OSBPL6 antibody detected the OSBPL6 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BZF3
Other Accession NP_665682.1, NP_115912.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 106306 Da
Antigen Region 769-796 aa
Additional Information
Gene ID 114880
Other Names Oxysterol-binding protein-related protein 6, ORP-6, OSBP-related protein 6, OSBPL6, ORP6
Target/Specificity This OSBPL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 769-796 amino acids from the C-terminal region of human OSBPL6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOSBPL6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OSBPL6
Synonyms ORP6
Function Weakly binds 25-hydroxycholesterol.
Cellular Location Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope Cell membrane; Peripheral membrane protein
Tissue Location Expressed in brain and striated muscle (at protein level) (PubMed:14593528). Widely expressed (PubMed:11735225). Expressed in skeletal muscle (PubMed:14593528)
Research Areas
Citations (0)

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Background

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified.

References

Maestrini, E., et al. Mol. Psychiatry 15(9):954-968(2010)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Lehto, M., et al. Cell Tissue Res. 315(1):39-57(2004)
Jaworski, C.J., et al. Genomics 78(3):185-196(2001)
Lehto, M., et al. J. Lipid Res. 42(8):1203-1213(2001)

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$ 295.00
$ 99.00
Cat# AP17475b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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