|Application ||WB, E|
|Other Accession||Q5FWT7, Q8BGR9, Q2KJD7, NP_659486.2|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||36805 Da|
|Antigen Region||222-248 aa|
|Other Names||Ubiquitin-like domain-containing CTD phosphatase 1, Nuclear proteasome inhibitor UBLCP1, UBLCP1|
|Target/Specificity||This UBLCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-248 amino acids from the C-terminal region of human UBLCP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UBLCP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.|
|Cellular Location||Nucleus. Note=Colocalizes with nuclear proteasomes|
|Tissue Location||Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
UBLCP1 may specifically dephosphorylate 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit.
Nair, R.P., et al. Nat. Genet. 41(2):199-204(2009)
Zheng, H., et al. Biochem. Biophys. Res. Commun. 331(4):1401-1407(2005)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.