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GGT6 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GGT6 Antibody (N-term) AP17485A
    GGT6 Antibody (N-term) (Cat. #AP17485a) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GGT6 antibody detected the GGT6 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6P531
Other Accession NP_001116362.1, NP_699169.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 50509 Da
Antigen Region 23-49 aa
Additional Information
Gene ID 124975
Other Names Gamma-glutamyltransferase 6, GGT 6, Gamma-glutamyltranspeptidase 6, Glutathione hydrolase 6, Gamma-glutamyltransferase 6 heavy chain, Gamma-glutamyltransferase 6 light chain, GGT6
Target/Specificity This GGT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human GGT6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGGT6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GGT6 (HGNC:26891)
Function Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors.
Cellular Location Membrane {ECO:0000250|UniProtKB:P19440}; Single- pass type II membrane protein {ECO:0000250|UniProtKB:P07314}
Research Areas
Citations (0)
citation

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Background

GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).

References

Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)

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$ 182.50
$ 70.00
Cat# AP17485A
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