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ACTA1/?-actin Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP17487b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP17487b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
ACTA1/?-actin Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | P68133 |
| Other Accession | P60010, P68136, P68135, P68137, P68134, P68139, P68138, P63269, P63268, P63267, P63270, Q5E9B5, A2BDB0, P63259, P63260, P63261, Q5ZMQ2, P63258, P04751, P68035, P68033, P68032, P68034, Q3ZC07, O93400, P60711, P29751, Q6QAQ1, P60710, Q4R561, P60709, P48975; |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Drosophila, C.Elegans, Hamster, Mouse, Pig, Monkey, Rat, Rabbit, Xenopus, Yeast, Zebrafish |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 42051 Da |
ACTA1/?-actin Antibody (C-term) - Additional info | |
| Gene ID 58 | |
| Other Names ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-actin-1 | |
| Target/Specificity This ACTA1/?-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the C-terminal region of human ACTA1/?-actin. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACTA1/?-actin Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACTA1/?-actin Antibody (C-term) - Protein Information | |
| Name ACTA1 | |
| Synonyms ACTA | |
| Function Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | |
| Cellular Location Cytoplasm, cytoskeleton. | |
ACTA1/?-actin Antibody (C-term) - Related products
AM1965a: ACTA1 Antibody (Ascites)
AP14779b: ACTA1/?-actin Antibody (C-term)
AP17487b: ACTA1/?-actin Antibody (C-term)
ACTA1/?-actin Antibody (C-term) - Application data
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ACTA1/α-actin Antibody (C-term) (Cat. #AP17487b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ACTA1/α-actin antibody detected the ACTA1/α-actin protein (arrow).
ACTA1/?-actin Antibody (C-term) - Research Areas
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BACKGROUND
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
REFERENCES
Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010) : Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010) Yu, G., et al. J Clin Neurosci 17(6):766-769(2010) Yu, C.H., et al. PLoS ONE 5 (7), E11878 (2010) : Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)
