|Application ||WB, E|
|Calculated MW||66455 Da|
|Antigen Region||118-148 aa|
|Other Names||Zinc finger protein 10, Zinc finger protein KOX1, ZNF10, KOX1|
|Target/Specificity||This ZNF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-148 amino acids from the N-terminal region of human ZNF10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF10 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in transcriptional regulation.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein.
Lorenz, P., et al. Biol. Chem. 382(4):637-644(2001)
Peng, H., et al. J. Biol. Chem. 275(24):18000-18010(2000)
Moosmann, P., et al. Biol. Chem. 378(7):669-677(1997)
Moosmann, P., et al. Nucleic Acids Res. 24(24):4859-4867(1996)
Vissing, H., et al. FEBS Lett. 369 (2-3), 153-157 (1995) :
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