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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CHST10 Antibody (C-term)   

CHST10 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CHST10 Antibody (C-term) AP17499B
    CHST10 Antibody (C-term) (Cat. #AP17499b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CHST10 antibody detected the CHST10 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43529
Other Accession NP_004845.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42207 Da
Antigen Region 208-236 aa
Additional Information
Gene ID 9486
Other Names Carbohydrate sulfotransferase 10, 282-, HNK-1 sulfotransferase, HNK-1ST, HNK1ST, HuHNK-1ST, CHST10
Target/Specificity This CHST10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the C-terminal region of human CHST10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCHST10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CHST10
Function Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues In brain, it is expressed at higher level in the frontal lobe
Research Areas
Citations (0)

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Cell surface carbohydrates modulate a variety of cellular functions and are typically synthesized in a stepwise manner. HNK1ST plays a role in the biosynthesis of HNK1 (see MIM 151290), a neuronally expressed carbohydrate that contains a sulfoglucuronyl residue.


Zhao, X., et al. Cancer Res. 69(12):5218-5225(2009)
Kang, H.G., et al. J. Biol. Chem. 277(38):34766-34772(2002)
Ong, E., et al. J. Biol. Chem. 274(36):25608-25612(1999)
Ong, E., et al. J. Biol. Chem. 273(9):5190-5195(1998)

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$ 295.00
$ 99.00
Cat# AP17499B
(40 western blots)
Availability: In Stock
Bulk Size
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