|Application ||WB, E|
|Other Accession||Q8CI71, Q5ZKV9, NP_078829.1, NP_060137.2, F1LSG8|
|Predicted||Chicken, Mouse, Rat|
|Calculated MW||111174 Da|
|Antigen Region||904-930 aa|
|Other Names||Coiled-coil domain-containing protein 132, CCDC132, KIAA1861|
|Target/Specificity||This CCDC132 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-930 amino acids from the C-terminal region of human CCDC132.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCDC132 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).|
|Cellular Location||Recycling endosome|
|Tissue Location||Ubiquitous, with higher expression in brain and skeletal muscle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
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