|Application ||WB, E|
|Other Accession||NP_001163873.1, NP_001139206.2|
|Calculated MW||57335 Da|
|Antigen Region||11-39 aa|
|Other Names||Cell division cycle protein 20 homolog B, CDC20B|
|Target/Specificity||This CDC20B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human CDC20B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CDC20B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The timely destruction of key regulators through ubiquitin-mediated proteolysis ensures the orderly progression of the cell cycle. The APC (anaphase-promoting complex) is a major component of this degradation machinery and its activation is required for the execution of critical events. CDC20B has been implicated as a meiosis specific activator of APC and is required for sporulation in budding yeast.
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Ota, T., et al. Nat. Genet. 36(1):40-45(2004)
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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