|Application ||WB, E|
|Other Accession||Q8CGZ0, NP_006378.3|
|Calculated MW||103702 Da|
|Antigen Region||877-903 aa|
|Other Names||Calcium homeostasis endoplasmic reticulum protein, ERPROT 213-21, SR-related CTD-associated factor 6, CHERP (HGNC:16930)|
|Target/Specificity||This CHERP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 877-903 amino acids from the C-terminal region of human CHERP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CHERP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in calcium homeostasis, growth and proliferation.|
|Cellular Location||Cytoplasm Cytoplasm, perinuclear region Endoplasmic reticulum Note=Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1|
|Tissue Location||Expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells.|
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Provided below are standard protocols that you may find useful for product applications.
CHERP is involved in calcium homeostasis, growth and proliferation.
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Laplante, J.M., et al. Biochem. J. 348 PT 1, 189-199 (2000) :
Imbert, G., et al. Nat. Genet. 14(3):285-291(1996)
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