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CLEC4D Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CLEC4D Antibody (Center) AP17517c
    CLEC4D Antibody (Center) (Cat. #AP17517c) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CLEC4D antibody detected the CLEC4D protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8WXI8
Other Accession NP_525126.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24704 Da
Antigen Region 126-153 aa
Additional Information
Gene ID 338339
Other Names C-type lectin domain family 4 member D, C-type lectin superfamily member 8, C-type lectin-like receptor 6, CLEC-6, CLEC4D, CLECSF8, MCL
Target/Specificity This CLEC4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-153 amino acids from the Central region of human CLEC4D.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLEC4D Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC4D
Synonyms CLECSF8, MCL
Function Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression is confined mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma.
Research Areas
Citations (0)

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Background

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

References

Flornes, L.M., et al. Immunogenetics 56(7):506-517(2004)
Arce, I., et al. Eur. J. Immunol. 34(1):210-220(2004)
Ebner, S., et al. Proteins 53(1):44-55(2003)
Drickamer, K. Curr. Opin. Struct. Biol. 9(5):585-590(1999)

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$ 295.00
$ 99.00
Cat# AP17517c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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