|Application ||WB, E|
|Calculated MW||21740 Da|
|Antigen Region||7-34 aa|
|Other Names||DNA damage-inducible transcript 4-like protein, HIF-1 responsive protein RTP801-like, Protein regulated in development and DNA damage response 2, REDD-2, DDIT4L, REDD2, RTP801L|
|Target/Specificity||This DDIT4L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human DDIT4L.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DDIT4L Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.|
|Tissue Location||Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Koga, Y., et al. Genome Res. 19(8):1462-1470(2009)
Imen, J.S., et al. Free Radic. Biol. Med. 46(10):1404-1410(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Corradetti, M.N., et al. J. Biol. Chem. 280(11):9769-9772(2005)
Cuaz-Perolin, C., et al. Arterioscler. Thromb. Vasc. Biol. 24(10):1830-1835(2004)
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