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FBXO16 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IX29 |
| Other Accession | NP_758954.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 34588 Da |
| Antigen Region | 245-272 aa |
| Gene ID | 157574 |
|---|---|
| Other Names | F-box only protein 16, FBXO16, FBX16 |
| Target/Specificity | This FBXO16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-272 amino acids from the C-terminal region of human FBXO16. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FBXO16 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FBXO16 |
|---|---|
| Synonyms | FBX16 |
| Function | Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. |
| Tissue Location | Expressed in heart, spleen and colon. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class.
References
Cheng, H., et al. Mol. Cells 14(1):56-59(2002)
Cenciarelli, C., et al. Curr. Biol. 9(20):1177-1179(1999)
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