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UBE2Q1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - UBE2Q1 Antibody (N-term) AP17537a
    UBE2Q1 Antibody (N-term) (Cat. #AP17537a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the UBE2Q1 antibody detected the UBE2Q1 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q7Z7E8
Other Accession NP_060052.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46127 Da
Antigen Region 78-104 aa
Additional Information
Gene ID 55585
Other Names Ubiquitin-conjugating enzyme E2 Q1, Protein NICE-5, Ubiquitin carrier protein Q1, Ubiquitin-protein ligase Q1, UBE2Q1, NICE5, UBE2Q
Target/Specificity This UBE2Q1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-104 amino acids from the N-terminal region of human UBE2Q1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUBE2Q1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE2Q1
Synonyms NICE5, UBE2Q
Function Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:22496338). May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q7TSS2}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q7TSS2}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q7TSS2}
Tissue Location Widely expressed..
Research Areas
Citations (0)
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Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart.

References

Wassler, M.J., et al. Stem Cells 26(8):2006-2018(2008)
Grelle, G., et al. Mol. Cell Proteomics 5(2):234-244(2006)
Wistow, G., et al. Mol. Vis. 8, 205-220 (2002) :
Marenholz, I., et al. Genome Res. 11(3):341-355(2001)

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$ 182.50
$ 70.00
Cat# AP17537a
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