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ZBTB4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZBTB4 Antibody (Center) AP17542c
    ZBTB4 Antibody (Center) (Cat. #AP17542c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ZBTB4 antibody detected the ZBTB4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P1Z0
Other Accession NP_001122305.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 105114 Da
Antigen Region 401-430 aa
Additional Information
Gene ID 57659
Other Names Zinc finger and BTB domain-containing protein 4, KAISO-like zinc finger protein 1, KAISO-L1, ZBTB4, KIAA1538
Target/Specificity This ZBTB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human ZBTB4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZBTB4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB4
Synonyms KIAA1538
Function Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688).
Cellular Location Nucleus. Chromosome. Note=Localizes to chromocenters.
Citations (0)

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ZBTB4 may be involved in transcriptional regulation.


Sasai, N., et al. Nucleic Acids Res. 38(15):5015-5022(2010)
Yamada, D., et al. Oncogene 28(27):2535-2544(2009)
Weber, A., et al. EMBO J. 27(11):1563-1574(2008)
Filion, G.J., et al. Mol. Cell. Biol. 26(1):169-181(2006)

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$ 295.00
$ 99.00
Cat# AP17542c
(40 western blots)
Availability: In Stock
Bulk Size
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