|Application ||WB, E|
|Other Accession||Q9BE71, NP_065788.1|
|Calculated MW||84731 Da|
|Antigen Region||630-659 aa|
|Other Names||Leucine-rich repeat and fibronectin type-III domain-containing protein 2, Synaptic adhesion-like molecule 1, LRFN2, KIAA1246, SALM1|
|Target/Specificity||This LRFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 630-659 amino acids from the C-terminal region of human LRFN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRFN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane|
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Provided below are standard protocols that you may find useful for product applications.
LRFN2 promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity).
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Morimura, N., et al. Gene 380(2):72-83(2006)
Wang, C.Y., et al. J. Neurosci. 26(8):2174-2183(2006)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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