|Application ||WB, E|
|Other Accession||Q9BE71, NP_065788.1|
|Calculated MW||84731 Da|
|Antigen Region||630-659 aa|
|Other Names||Leucine-rich repeat and fibronectin type-III domain-containing protein 2, Synaptic adhesion-like molecule 1, LRFN2, KIAA1246, SALM1|
|Target/Specificity||This LRFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 630-659 amino acids from the C-terminal region of human LRFN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRFN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
LRFN2 promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity).
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Morimura, N., et al. Gene 380(2):72-83(2006)
Wang, C.Y., et al. J. Neurosci. 26(8):2174-2183(2006)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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