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GLDN Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GLDN Antibody (Center) AP17551c
    GLDN Antibody (Center) (Cat. #AP17551c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GLDN antibody detected the GLDN protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6ZMI3
Other Accession NP_861454.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 58957 Da
Antigen Region 271-299 aa
Additional Information
Gene ID 342035
Other Names Gliomedin, GLDN, COLM
Target/Specificity This GLDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-299 amino acids from the Central region of human GLDN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGLDN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLDN
Synonyms COLM
Function Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier (By similarity).
Cellular Location Cell membrane; Single-pass type II membrane protein. Note=Localizes to the nodes of Ranvier.
Tissue Location Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system.
Research Areas
Citations (0)

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Background

GLDN plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier (By similarity).

References

Eshed, Y., et al. Neuron 47(2):215-229(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Graveel, C.R., et al. Oncogene 22(11):1730-1736(2003)

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$ 295.00
$ 99.00
Cat# AP17551c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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