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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   DUSP6 Antibody (N-term)   

DUSP6 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DUSP6 Antibody (N-term) AP17558A
    DUSP6 Antibody (N-term) (Cat. #AP17558a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DUSP6 antibody detected the DUSP6 protein (arrow).
  • WB - DUSP6 Antibody (N-term) AP17558A
    DUSP6 Antibody (N-term) (Cat. #AP17558a) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the DUSP6 antibody detected the DUSP6 protein (arrow).
  • WB - DUSP6 Antibody (N-term) AP17558A
    Western blot analysis of DUSP6 (arrow) using rabbit polyclonal DUSP6 Antibody (N-term) (Cat. #AP17558a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DUSP6 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16828
Other Accession Q2KJ36, NP_073143.2, NP_001937.2
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42320 Da
Antigen Region 59-88 aa
Additional Information
Gene ID 1848
Other Names Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3, DUSP6, MKP3, PYST1
Target/Specificity This DUSP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human DUSP6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDUSP6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUSP6
Synonyms MKP3, PYST1
Function Inactivates MAP kinases. Has a specificity for the ERK family.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.


Chiappinelli, K.B., et al. Gynecol. Oncol. 119(1):146-150(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Nunes-Xavier, C.E., et al. J. Biol. Chem. 285(34):26417-26430(2010)
Zhang, Z., et al. Carcinogenesis 31(4):577-586(2010)
Wang, Z., et al. Mol. Vis. 16, 1696-1704 (2010) :

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$ 295.00
$ 99.00
Cat# AP17558A
(40 western blots)
Availability: In Stock
Bulk Size
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