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EVI2B Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - EVI2B Antibody (Center) AP17567C
    EVI2B Antibody (Center) (Cat. #AP17567c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the EVI2B antibody detected the EVI2B protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P34910
Other Accession NP_006486.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 283-313 aa
Additional Information
Other Names Protein EVI2B, Ecotropic viral integration site 2B protein homolog, EVI-2B, CD361, EVI2B, EVDB
Target/Specificity This EVI2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the Central region of human EVI2B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEVI2B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EVI2B
Synonyms EVDB
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Bone marrow, peripheral blood mononuclear cells, fibroblasts and Epstein-Barr virus-transformed lymphoblastoid cell lines EMBL; M60830; AAA35816.1; -; Genomic_DNA EMBL; AK297087; BAH12493.1; -; mRNA EMBL; AC134669; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS11266.1; -. [P34910-1] PIR; A38445; A38445 RefSeq; NP_006486.3; NM_006495.3. [P34910-1] RefSeq; XP_005258003.1; XM_005257946.3. [P34910-2] UniGene; Hs.5509; - ProteinModelPortal; P34910; - STRING; 9606.ENSP00000333779; - iPTMnet; P34910; - PhosphoSitePlus; P34910; - SwissPalm; P34910; - BioMuta; EVI2B; - DMDM; 281185464; - EPD; P34910; - MaxQB; P34910; - PaxDb; P34910; - PeptideAtlas; P34910; - PRIDE; P34910; - DNASU; 2124; - Ensembl; ENST00000330927; ENSP00000333779; ENSG00000185862. [P34910-1] Ensembl; ENST00000577894; ENSP00000462682; ENSG00000185862. [P34910-1] GeneID; 2124; - KEGG; hsa:2124; - UCSC; uc002hgk.3; human. [P34910-1] CTD; 2124; - DisGeNET; 2124; - GeneCards; EVI2B; - H-InvDB; HIX0013696; - HGNC; HGNC:3500; EVI2B HPA; HPA007436; - HPA; HPA053383; - MIM; 158381; gene neXtProt; NX_P34910; - OpenTargets; ENSG00000185862; - PharmGKB; PA27914; - eggNOG; ENOG410IVU1; Eukaryota eggNOG; ENOG41118NF; LUCA GeneTree; ENSGT00390000009142; - HOGENOM; HOG000285986; - HOVERGEN; HBG051514; - InParanoid; P34910; - KO; K16854; - OMA; HTSAGQP; - OrthoDB; EOG091G0GGD; - PhylomeDB; P34910; - TreeFam; TF336167; - BioCyc; ZFISH:G66-33877-MONOMER; - GeneWiki; EVI2B; - GenomeRNAi; 2124; - PRO; PR:P34910; - Proteomes; UP000005640; Chromosome 17 Bgee; ENSG00000185862; - CleanEx; HS_EVI2B; - Genevisible; P34910; HS GO; GO:0005887; C:integral component of plasma membrane; TAS:ProtInc InterPro; IPR033239; EVI2B PANTHER; PTHR15384; PTHR15384; 1 ProDom; PD140898; PD140898; 1 1: Evidence at protein level; Alternative splicing; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Signal; Transmembrane; Transmembrane helix SIGNAL 1 21 CHAIN 22 448 Protein EVI2B /FTId=PRO_0000021213 TOPO_DOM 22 202 Extracellular. TRANSMEM 203 226 Helical. TOPO_DOM 227 448 Cytoplasmic. MOD_RES 249 249 Phosphothreonine {ECO:0000250|UniProtKB:Q8VD58} MOD_RES 268 268 Phosphoserine MOD_RES 271 271 Phosphoserine MOD_RES 278 278 Phosphoserine {ECO:0000250|UniProtKB:Q8VD58} MOD_RES 294 294 Phosphoserine CARBOHYD 16 16 N-linked (GlcNAc...). CARBOHYD 50 50 N-linked (GlcNAc...). CARBOHYD 114 114 N-linked (GlcNAc...). VAR_SEQ 1 1 M -> MLFRYAEKITRKYSEM (in isoform 2) /FTId=VSP_056461 VARIANT 53 53 G -> R (in dbSNP:rs9903564) /FTId=VAR_056871 CONFLICT 37 37 F -> Y (in Ref. 1; AAA35816) SEQUENCE 448 AA; 48666 MW; 5BF2DC46798577E3 CRC64; MDPKYFILIL FCGHLNNTFF SKTETITTEK QSQPTLFTSS MSQVLANSQN TTGNPLGQPT QFSDTFSGQS ISPAKVTAGQ PTPAVYTSSE KPEAHTSAGQ PLAYNTKQPT PIANTSSQQA VFTSARQLPS ARTSTTQPPK SFVYTFTQQS SSVQIPSRKQ ITVHNPSTQP TSTVKNSPRS TPGFILDTTS NKQTPQKNNY NSIAAILIGV LLTSMLVAII IIVLWKCLRK PVLNDQNWAG RSPFADGETP DICMDNIREN EISTKRTSII SLTPWKPSKS TLLADDLEIK LFESSENIED SNNPKTEKIK DQVNGTSEDS ADGSTVGTAV SSSDDADLPP PPPLLDLEGQ ESNQSDKPTM TIVSPLPNDS TSLPPSLDCL NQDCGDHKSE IIQSFPPLDS LNLPLPPVDF MKNQEDSNLE IQCQEFSIPP NSDQDLNESL PPPPAELL
Research Areas
Citations (0)

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Background

EVI2B (Ecotropic viral integration site 2B) may function as an oncogene in retrovirus-induced myeloid tumors and may have a role in leukemogenesis.

References

Douglas, J., et al. Nat. Genet. 39(8):963-965(2007)
Xu, G., et al. Genomics 13(3):537-542(1992)
Wallace, M.R., et al. Nature 353(6347):864-866(1991)
Cawthon, R.M., et al. Genomics 9(3):446-460(1991)
Viskochil, D., et al. Mol. Cell. Biol. 11(2):906-912(1991)

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$ 295.00
$ 99.00
Cat# AP17567C
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(40 western blots)
Availability: In Stock
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