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>   home   >   Products   >   Primary Antibodies   >   CREBZF Antibody (C-term)   

CREBZF Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CREBZF Antibody (C-term) AP17569b
    CREBZF Antibody (C-term) (Cat. #AP17569b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CREBZF antibody detected the CREBZF protein (arrow).
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NS37
Other Accession Q91ZR3, NP_001034707.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37134 Da
Antigen Region 280-309 aa
Additional Information
Gene ID 58487
Other Names CREB/ATF bZIP transcription factor, Host cell factor-binding transcription factor Zhangfei, HCF-binding transcription factor Zhangfei, CREBZF, ZF
Target/Specificity This CREBZF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human CREBZF.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCREBZF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CREBZF
Synonyms ZF
Function Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1- dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Cellular Location Nucleus. Note=Colocalizes in promyelocytic leukemia protein nuclear bodies (PML-NB) with CREB3 and HCFC1
Tissue Location In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
Citations (0)

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Background

Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.

References

Xie, Y.B., et al. J. Biol. Chem. 284(42):28762-28774(2009)
Valderrama, X., et al. J. Neurooncol. 91(1):7-17(2009)
Xie, Y.B., et al. Biochem. J. 416(3):463-473(2008)
Valderrama, X., et al. J. Neurovirol. 14(5):425-436(2008)
Hogan, M.R., et al. FEBS Lett. 580(1):58-62(2006)

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$ 295.00
$ 99.00
Cat# AP17569b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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