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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ALS2CL Antibody (Center)   

ALS2CL Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ALS2CL Antibody (Center) AP17574c
    ALS2CL Antibody (Center) (Cat. #AP17574c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ALS2CL antibody detected the ALS2CL protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q60I27
Other Accession NP_001177636.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 107748 Da
Antigen Region 349-377 aa
Additional Information
Gene ID 259173
Other Names ALS2 C-terminal-like protein, ALS2CL
Target/Specificity This ALS2CL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of human ALS2CL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALS2CL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.
Cellular Location Cytoplasm. Note=Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells
Tissue Location Expressed in heart and kidney.
Research Areas
Citations (0)

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ALS2CL acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.


Suzuki-Utsunomiya, K., et al. Biochem. Biophys. Res. Commun. 354(2):491-497(2007)
Hadano, S., et al. FEBS Lett. 575 (1-3), 64-70 (2004) :

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$ 295.00
$ 99.00
Cat# AP17574c
(40 western blots)
Availability: In Stock
Bulk Size
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