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GPR22 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q99680 |
| Other Accession | Q8BZL4, NP_005286.2, D4A3U0 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49265 Da |
| Antigen Region | 122-148 aa |
| Gene ID | 2845 |
|---|---|
| Other Names | Probable G-protein coupled receptor 22, GPR22 |
| Target/Specificity | This GPR22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human GPR22. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPR22 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR22 (HGNC:4477) |
|---|---|
| Function | Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway (PubMed:18539757). May be involved in ciliogenesis (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:D4A3U0}; Multi-pass membrane protein |
| Tissue Location | High expression in adult and fetal heart tissue (PubMed:18539757). Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions (PubMed:9073069, PubMed:18539757). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. [provided by RefSeq].
References
Kerkhof, H.J., et al. Arthritis Rheum. 62(2):499-510(2010)
Adams, J.W., et al. Am. J. Physiol. Heart Circ. Physiol. 295 (2), H509-H521 (2008) :
Lee, J., et al. FASEB J. 19(10):1356-1358(2005)
O'Dowd, B.F., et al. Gene 187(1):75-81(1997)
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