|Application ||WB, E|
|Other Accession||Q9D0I8, A4FV84, NP_057267.2|
|Calculated MW||27560 Da|
|Antigen Region||46-72 aa|
|Other Names||mRNA turnover protein 4 homolog, MRTO4, C1orf33, MRT4|
|Target/Specificity||This MRTO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 amino acids from the N-terminal region of human MRTO4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MRTO4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|
|Cellular Location||Nucleus, nucleolus Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq].
Michalec, B., et al. Int. J. Biochem. Cell Biol. 42(5):736-748(2010)
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)
Andersen, J.S., et al. Curr. Biol. 12(1):1-11(2002)
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